Christina Applegate knows what Giuliana Rancic is going through, and says she'll be there if the E! host - who has breast cancer - ever wants to talk.

After ABC announced the show's cancellation, fans of "Samantha Who?" have been figuring out ways to get their voice heard by the network. An online petition has been started to save the comedy which is being pushed by no other than the show's star, Christina Applegate.

Christina Applegate feels like she is "dying in the desert." The "Samantha Who?" actress is planning to embark on a quest for self fulfillment this year, comparing herself to a desperate traveler in scorching conditions.

Christina Applegate, who had a double mastectomy in July, is to undergo reconstructive surgery on her 37th birthday.

Christina Applegate can't wait for new "cute boobs" after having a double mastectomy.

Christina Applegate has been diagnosed with breast cancer. The 36-year-old "Friends" star has an early form of the disease and is expected to make a full recovery, her spokesperson has revealed.

Christina Applegate is "profoundly saddened" by the death of her on-off boyfriend Lee Grivas. The 'Samantha Who' star - who dated 26-year-old Lee at various points throughout the last two years - was not with the aspiring photographer at the time of his death, but says she is stunned by the news.