Chelsea Handler says she could be done with "Chelsea Lately"

Los Angeles, CA, United States (AHN Entertainment) - Chelsea Handler got to where she is today thanks to her books about one-night stands and lies she's told, her penchant for vodka, and her deadpan one-liners on Hollywood messes like Lindsay Lohan and Amy Winehouse. But she says she can't do it forever.

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Handler's contract with E! is up at the 2012 and she doesn't see herself talking about celebrities' latest rehab trips at a roundtable on "Chelsea Lately," which earns a million devoted viewers a night, for another five years. She sees herself doing something a little more cerebral.

"I want to do something that's going to utilize my brain a little more than this show," Chelsea Handler told The Hollywood Reporter in their new cover story. "If 'Lately' is the show that I'm going to do, it's going to change. But it may turn out that I'm done with it altogether I can't keep doing the same thing; my brain is bleeding. I want to do something that's more mindful and isn't celebrity-centered."

"I want to do something people aren't expecting from me," she said. "I want to educate people and deliver news that isn't just surrounded by Charlie Sheen. I'd like to be able to do the serious stuff in conjunction with the comedy. I'd like to make an impact and have more responsibility than I do now."

The first steps are "After Lately," the pseudo-reality show based on the inner workings of her "Chelsea Lately" staff," which was just renewed for a second season, and the NBC show "Are You There Vodka? It's Me, Chelsea," based on her best-selling book which she serves as Executive Producer.

But we just lost Oprah, girl. We're not ready for the farewell episodes of "Chelsea Lately" just yet.

"I'm not looking to totally bail on E! They've done a lot for me, and I like it here," Handler said. " If you take away the Kardashians."